
United are assessing the issue, but Sesko is thought to have felt some discomfort in his shin again.
The 23-year-old did not play a single minute in pre-season as he recovered from the shin injury. Sesko aggravated the issue against Liverpool in May, which kept him out for the final few weeks of the season.
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To get it, it's a simple one-two punch.
Sesko suggested the issue was behind him when he spoke to reporters after United's win against Sabah in the Champions League.
"I got a kick last season, but it was also a little bit of an overload from myself," Sesko said, referring to a challenge from Liverpool defender Ibrahima Konate in May.
"It was basically just to make sure that it doesn't get worse because this was kind of a problem.
"We just needed a little bit longer, longer than usual, because if you start too early, it might appear again. And I think waiting a little bit longer was a great decision, and now it's healed, so it's perfect."
Carrick has picked a striker-less attack of Marcus Rashford, Matheus Cunha and Bryan Mbeumo in the absence of Sesko.